Biologically active components in horse chestnut (aescin), grape seeds (proanthocyanidins) Seville orange (gesperidin), ginkgo biloba (flavonoglycosides) increase vein and venous valve tone, improve circulation through both large vessels and capillaries; they have anti-oxidant, anti-inflammatory, vessel-strengthening and lymph-draining activity, relieve swelling.
Troxerutin has a venotonic activity, reduces excess capillary leakage, strengthens and tones the capillaries. Troxerutin reduces pathologic changes related to venous incompetence: swelling, pain, inadequate tissue trophism.
Lady's mantle, melilot, willow bark and oat bark extracts contain flavonoids and tannins, strengthen vascular walls and have anti-inflammatory effect.
Vitamin E and vitamin A are strong anti-oxidants, they protect cellular membranes against oxidative stress, improve metabolism and cell regeneration, stimulate capillary circulation, reduce capillary brittlenes and leakage, maintain vascular wall elasticity; they also have anti-inflammatory activity.
Menthol facilitates fast penetration of the active components into tissues; it has freshening effect, relaxes leg muscles and creates a feeling of cooling and lightness.